Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL89595 | 0.95 | REN (0.58) | RENKCNH2 | |
| SCHEMBL8235655 | 0.90 | REN (0.54) | RENKCNH2 | |
| SCHEMBL89120 | 0.89 | REN (0.57) | RENKCNH2 | |
| SCHEMBL8235397 | 0.89 | REN (0.59) | RENKCNH2 | |
| SCHEMBL90345 | 0.89 | REN (0.57) | RENKCNH2 | |
| SCHEMBL89087 | 0.89 | REN (0.60) | RENKCNH2 | |
| SCHEMBL88999 | 0.89 | REN (0.60) | RENKCNH2 | |
| SCHEMBL89673 | 0.89 | REN (0.58) | RENKCNH2 | |
| SCHEMBL8235654 | 0.88 | REN (0.54) | RENKCNH2 | |
| SCHEMBL89287 | 0.88 | REN (0.57) | RENKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007077005-A1 | 3 , 5-SUBSTITΓUED PIPERIDINE COMPOUNDS AS RENIN INHIBITORS | NOVARTIS AG (CH) | 2007-07-12 | — | — | WO | disclosed |