Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.67 |
| ▸ | MEN1 | O00255 | 9/20 | 0.67 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | RORC | P51449 | 1/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | PDE5A | O76074 | 1/20 | 0.57 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5526966 | 0.85 | MEN1 (0.82) | KMT2AMEN1ABCG2MAPTTP53 | |
| SCHEMBL13945461 | 0.81 | MEN1 (0.97) | KMT2AMEN1ABCG2MAPTTP53 | |
| SCHEMBL3890403 | 0.81 | MAPT (0.83) | KMT2AMEN1ABCG2MAPTTP53 | |
| SCHEMBL5532972 | 0.80 | MAPT (0.69) | KMT2AMEN1ABCG2MAPTTP53 | |
| SCHEMBL7280956 | 0.77 | ABCG2 (1.00) | KMT2AMEN1ABCG2L3MBTL1ABCB1 | |
| SCHEMBL13945465 | 0.76 | MEN1 (0.82) | KMT2AMEN1ABCG2MAPTTP53 | |
| SCHEMBL22201667 | 0.76 | ABCG2 (0.67) | KMT2AMEN1ABCG2MAPTTP53 | |
| SCHEMBL1083771 | 0.75 | MEN1 (0.98) | KMT2AMEN1ABCG2MAPTTP53 | |
| SCHEMBL8094111 | 0.73 | MAPT (0.67) | KMT2AMEN1ABCG2MAPTTP53 | |
| SCHEMBL16404300 | 0.72 | ABCG2 (0.65) | KMT2AMEN1ABCG2MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071055-A1 | COMPOSITIONS AND METHODS FOR MODULATING GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-06-28 | — | — | WO | disclosed |