Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | LATS1 | O95835 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | GSK3A | P49840 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201666 | 0.87 | ALDH1A1 (0.60) | ABCG2MAPTABCB1SMN1; SMN2LATS1 | |
| SCHEMBL22201579 | 0.83 | ABCG2 (0.85) | ABCG2MAPTABCB1SMN1; SMN2LATS1 | |
| SCHEMBL22201606 | 0.81 | TGFBR1 (0.66) | MAPTALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL26177129 | 0.78 | LATS1 (1.00) | ABCG2MAPTABCB1SMN1; SMN2LATS1 | |
| SCHEMBL8094111 | 0.77 | MAPT (0.67) | ABCG2MAPTABCB1SMN1; SMN2ALDH1A1 | |
| SCHEMBL414358 | 0.77 | CYP1A2 (1.00) | ABCG2MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL16404300 | 0.76 | ABCG2 (0.65) | ABCG2MAPTABCB1SMN1; SMN2ALDH1A1 | |
| SCHEMBL16404488 | 0.76 | ABCG2 (0.65) | ABCG2MAPTABCB1SMN1; SMN2LMNA | |
| SCHEMBL8236002 | 0.76 | KMT2A (0.67) | ABCG2MAPTABCB1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8096433 | 0.75 | ABCG2 (0.83) | ABCG2MAPTABCB1SMN1; SMN2LATS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |