Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.34 |
| ▸ | FSHR | P23945 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1837607 | 0.80 | ALOX15 (0.39) | TSHRCYP2C19LMNACYP1A2KCNH2 | |
| SCHEMBL1812214 | 0.80 | ALOX15 (0.39) | TSHRCYP2C19LMNACYP1A2KCNH2 | |
| SCHEMBL234349 | 0.80 | TSHR (0.34) | TSHRFSHRCYP3A4ABCB11LMNA | |
| Hydrochloric Acid SCHEMBL1812212 | 0.78 | SMN1; SMN2 (0.38) | CYP3A4CYP1A2MEN1MAPK1PMP22 | |
| Hydrochloric Acid SCHEMBL242120 | 0.78 | SMN1; SMN2 (0.38) | CYP3A4CYP1A2MEN1MAPK1PMP22 | |
| SCHEMBL12306234 | 0.78 | TSHR (0.36) | TSHRFSHRCYP3A4ABCB11LMNA | |
| SCHEMBL2507803 | 0.78 | ALOX15 (0.41) | LMNACYP1A2KCNH2HSD17B10MEN1 | |
| SCHEMBL17683993 | 0.77 | TSHR (0.39) | TSHRCYP2C19CYP3A4ABCB11LMNA | |
| SCHEMBL3296871 | 0.76 | TSHR (0.35) | TSHRCYP2C19MAPK1NPSR1ADORA3 | |
| SCHEMBL22874559 | 0.76 | TSHR (0.35) | TSHRCYP2C19MAPK1NPSR1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007110727-A2 | AMIDE STABILIZED HYDROXYETHYLAMINES | PFIZER PRODUCTS INC. (US) | 2007-10-04 | — | — | WO | disclosed |