Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 17/20 | 0.61 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.42 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.42 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2812970 | 0.96 | IL2 (0.66) | IL2STIM1ORAI1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2811428 | 0.95 | IL2 (0.65) | IL2STIM1ORAI1NPC1RAB9A | |
| SCHEMBL8261671 | 0.90 | IL2 (0.66) | IL2STIM1ORAI1 | |
| SCHEMBL4762567 | 0.86 | IL2 (0.71) | IL2STIM1ORAI1 | |
| SCHEMBL2812935 | 0.85 | IL2 (0.54) | IL2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2813897 | 0.84 | IL2 (0.53) | IL2NPC1RAB9A | |
| SCHEMBL5554286 | 0.83 | IL2 (0.69) | IL2STIM1ORAI1ORAI2 | |
| SCHEMBL2814805 | 0.83 | IL2 (0.53) | IL2NPC1RAB9A | |
| SCHEMBL2813970 | 0.82 | CYP11B2 (0.47) | IL2NPC1RAB9A | |
| SCHEMBL2813079 | 0.80 | IL2 (0.44) | IL2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007089904-A2 | PYRIDYLPHENYL COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2007-08-09 | — | — | WO | disclosed |