Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.47 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3616231 | 0.91 | STS (0.48) | STSUSP30ANO1MEN1KMT2A | |
| SCHEMBL13502918 | 0.91 | STS (0.48) | STSUSP30ANO1MEN1KMT2A | |
| SCHEMBL3616230 | 0.91 | STS (0.48) | STSUSP30ANO1MEN1KMT2A | |
| SCHEMBL3612263 | 0.85 | REN (0.52) | STSANO1TP53REN | |
| SCHEMBL3610871 | 0.85 | REN (0.52) | STSANO1TP53REN | |
| SCHEMBL13502919 | 0.84 | REN (0.43) | STSUSP30ANO1MEN1KMT2A | |
| SCHEMBL3620859 | 0.84 | REN (0.43) | STSUSP30ANO1MEN1KMT2A | |
| SCHEMBL3620857 | 0.84 | REN (0.43) | STSUSP30ANO1MEN1KMT2A | |
| SCHEMBL13502922 | 0.83 | REN (0.54) | REN | |
| SCHEMBL3615881 | 0.83 | FNTA (0.42) | STSUSP30ANO1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007070201-A1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |