Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | TP53 | P04637 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | STAT1 | P42224 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10473961 | 0.85 | ALDH1A1 (0.60) | ALDH1A1MAPTALOX15HPGDL3MBTL1 | |
| SCHEMBL10472913 | 0.85 | ALDH1A1 (0.60) | ALDH1A1MAPTALOX15HPGDL3MBTL1 | |
| SCHEMBL10472733 | 0.83 | ALDH1A1 (0.57) | ALDH1A1MAPTALOX15HPGDL3MBTL1 | |
| SCHEMBL614472 | 0.82 | NPC1 (0.66) | ALDH1A1MAPTALOX15HPGDL3MBTL1 | |
| SCHEMBL610702 | 0.82 | NPC1 (0.66) | ALDH1A1MAPTALOX15HPGDL3MBTL1 | |
| SCHEMBL609043 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MAPTALOX15HPGDL3MBTL1 | |
| SCHEMBL611035 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MAPTALOX15HPGDL3MBTL1 | |
| SCHEMBL8246379 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPTALOX15HPGDL3MBTL1 | |
| SCHEMBL611868 | 0.80 | MAPT (0.68) | ALDH1A1MAPTALOX15HPGDL3MBTL1 | |
| SCHEMBL21320271 | 0.80 | NPC1 (0.56) | ALDH1A1MAPTNPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007036733-A1 | PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS, AND THEIR USE AS PDE4 INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-04-05 | — | — | WO | disclosed |