Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12385819 | 1.00 | MEN1 (0.60) | MEN1KMT2ATDP1ALDH1A1L3MBTL1 | |
| SCHEMBL13818485 | 1.00 | MEN1 (0.60) | MEN1KMT2ATDP1ALDH1A1L3MBTL1 | |
| SCHEMBL15014602 | 0.90 | NPSR1 (0.68) | MEN1KMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL16301341 | 0.90 | NPSR1 (0.68) | MEN1KMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL762416 | 0.89 | KMT2A (0.74) | MEN1KMT2ATDP1ALDH1A1L3MBTL1 | |
| Methylamine SCHEMBL27601189 | 0.86 | KMT2A (0.70) | MEN1KMT2ATDP1ALDH1A1L3MBTL1 | |
| SCHEMBL13007126 | 0.85 | L3MBTL1 (0.61) | MEN1KMT2AALDH1A1L3MBTL1TP53 | |
| SCHEMBL6882681 | 0.85 | EBP (0.63) | MEN1KMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL13818486 | 0.85 | EBP (0.63) | MEN1KMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL8185779 | 0.85 | EBP (0.63) | MEN1KMT2ATDP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3262036-B1 | THERAPEUTIC PYRIDAZINE COMPOUNDS AND USES THEREOF | GENENTECH INC (US) | 2023-09-13 | — | — | EP | disclosed |
| WO-2007094513-A2 | CYCLIC AMINE COMPOUND AND USE THEREOF FOR THE PROPHYLAXIS OR TREATMENT OF HYPERTENSION | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-08-23 | — | — | WO | disclosed |