Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941669 | 0.78 | KDM4E (0.51) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL3063647 | 0.73 | KDM4E (0.67) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL4225208 | 0.68 | MAPT (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL27957392 | 0.66 | ALDH1A1 (1.00) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL9824755 | 0.66 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1MCL1HPGD | |
| SCHEMBL27970803 | 0.65 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL28591593 | 0.63 | ALDH1A1 (0.69) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL8133617 | 0.63 | MCL1 (0.57) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL12525977 | 0.63 | NSD2 (0.54) | MEN1KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL27970860 | 0.62 | TSHR (0.49) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071738-A1 | CONDENSED HETEROCYCLIC COMPOUNDS USEFUL AS DPP-IV INHIBITORS | NOVARTIS AG (CH) | 2007-06-28 | — | — | WO | disclosed |