Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.76 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4235984 | 0.87 | DPP4 (0.72) | DPP4KCNH2ALDH1A1TSHRLMNA | |
| SCHEMBL8237509 | 0.87 | DPP4 (0.72) | DPP4KCNH2ALDH1A1TSHRLMNA | |
| SCHEMBL4229687 | 0.86 | DPP4 (1.00) | DPP4KCNH2 | |
| SCHEMBL4229682 | 0.86 | DPP4 (1.00) | DPP4KCNH2 | |
| SCHEMBL8230451 | 0.81 | DPP4 (0.62) | DPP4KCNH2ALDH1A1TSHRLMNA | |
| SCHEMBL4669794 | 0.80 | DPP4 (1.00) | DPP4KCNH2ALDH1A1TSHRLMNA | |
| SCHEMBL554515 | 0.80 | DPP4 (1.00) | DPP4KCNH2ALDH1A1TSHRLMNA | |
| SCHEMBL8236527 | 0.80 | DPP4 (0.65) | DPP4KCNH2 | |
| SCHEMBL13647411 | 0.79 | DPP4 (0.61) | DPP4KCNH2 | |
| SCHEMBL14422152 | 0.79 | DPP4 (0.61) | DPP4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071738-A1 | CONDENSED HETEROCYCLIC COMPOUNDS USEFUL AS DPP-IV INHIBITORS | NOVARTIS AG (CH) | 2007-06-28 | — | — | WO | disclosed |