Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8237262 | 0.84 | DPP4 (0.68) | DPP4KCNH2L3MBTL1 | |
| SCHEMBL8239570 | 0.83 | DPP4 (0.62) | DPP4L3MBTL1ALDH1A1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL4225083 | 0.83 | DPP4 (0.67) | DPP4KCNH2L3MBTL1 | |
| SCHEMBL8240496 | 0.82 | DPP4 (0.54) | DPP4KCNH2L3MBTL1ALDH1A1TSHR | |
| SCHEMBL8239848 | 0.81 | DPP4 (0.61) | DPP4KCNH2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4225103 | 0.81 | DPP4 (0.53) | DPP4KCNH2L3MBTL1ALDH1A1TSHR | |
| SCHEMBL8237497 | 0.81 | DPP4 (0.76) | DPP4KCNH2ALDH1A1TSHRMAPK1 | |
| SCHEMBL8230984 | 0.81 | DPP4 (0.69) | DPP4KCNH2 | |
| Hydrochloric Acid SCHEMBL4220187 | 0.80 | DPP4 (0.68) | DPP4KCNH2 | |
| SCHEMBL13780196 | 0.78 | DPP4 (0.52) | DPP4KCNH2L3MBTL1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071738-A1 | CONDENSED HETEROCYCLIC COMPOUNDS USEFUL AS DPP-IV INHIBITORS | NOVARTIS AG (CH) | 2007-06-28 | — | — | WO | disclosed |