Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.37 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 6/20 | 0.31 |
| ▸ | CA2 | P00918 | 6/20 | 0.31 |
| ▸ | CA4 | P22748 | 6/20 | 0.31 |
| ▸ | CA9 | Q16790 | 6/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | KLK7 | P49862 | 1/20 | 0.30 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13340978 | 0.89 | ABHD6 (0.42) | ABHD6DAGLAPARP1DPP4NR1H2 | |
| SCHEMBL3491419 | 0.81 | CA1 (0.36) | ABHD6DAGLACA1CA2CA4 | |
| SCHEMBL13340974 | 0.78 | ABHD6 (0.47) | ABHD6DAGLAPARP1DPP4NR1H2 | |
| SCHEMBL13340972 | 0.77 | ABHD6 (0.43) | ABHD6DAGLAPARP1DPP4NR1H2 | |
| SCHEMBL8235524 | 0.72 | ABHD6 (0.46) | ABHD6DAGLAPARP1DPP4NR1H2 | |
| SCHEMBL13340965 | 0.72 | ABHD6 (0.46) | ABHD6DAGLAPARP1DPP4NR1H2 | |
| SCHEMBL13340969 | 0.72 | ABHD6 (0.44) | ABHD6DAGLAPARP1DPP4NR1H2 | |
| SCHEMBL8230011 | 0.72 | ABHD6 (0.46) | ABHD6DAGLAPARP1DPP4NR1H2 | |
| SCHEMBL8230166 | 0.72 | ABHD6 (0.46) | ABHD6DAGLAPARP1DPP4NR1H2 | |
| SCHEMBL8113853 | 0.71 | ABHD6 (0.40) | ABHD6DAGLAPARP1DPP4NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007094513-A2 | CYCLIC AMINE COMPOUND AND USE THEREOF FOR THE PROPHYLAXIS OR TREATMENT OF HYPERTENSION | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-08-23 | — | — | WO | disclosed |