Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 18/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8236454 | 1.00 | HRH3 (0.56) | HRH3KCNH2MEN1KMT2A | |
| SCHEMBL4159411 | 0.90 | DRD2 (0.50) | HRH3 | |
| SCHEMBL9599380 | 0.89 | HRH3 (0.47) | HRH3KCNH2MEN1 | |
| SCHEMBL9598357 | 0.89 | TDP1 (0.46) | HRH3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9597870 | 0.86 | HRH3 (0.62) | HRH3KCNH2 | |
| SCHEMBL8228904 | 0.85 | HRH3 (0.44) | HRH3 | |
| SCHEMBL4171578 | 0.85 | HRH3 (0.37) | HRH3 | |
| SCHEMBL8237527 | 0.85 | HRH3 (0.42) | HRH3KCNH2MEN1 | |
| SCHEMBL13940150 | 0.84 | HRH3 (0.43) | HRH3KCNH2 | |
| SCHEMBL8940978 | 0.84 | HRH3 (0.37) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090017112-A1 | Compounds for Inhibiting Beta-Amyloid Production | ROSKAMP RESEARCH LLC (US) | 2009-01-15 | — | — | US | disclosed |
| US-20090017112-A1 | Compounds for Inhibiting Beta-Amyloid Production | ROSKAMP RESEARCH LLC (US) | 2009-01-15 | — | — | US | disclosed |
| WO-2007103683-A2 | COMPOUNDS FOR INHIBITING BETA-AMYLOID PRODUCTION | ROSKAMP RESEARCH LLC (US) | 2007-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090017112-A1 | Compounds for Inhibiting Beta-Amyloid Production | PSEN1, PSEN2, APP | HRH3 2768/4885KCNH2 4740/4885MEN1 3748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.