SCHEMBL823783

SCHEMBL823783

Cc1cc(F)c(F)cc1F

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.38
GPR3 P46089 1/20 0.37
DAO P14920 1/20 0.34
RAPGEF4 Q8WZA2 3/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
PTGS2 P35354 2/20 0.32
NFE2L2 Q16236 1/20 0.32
PTGS1 P23219 1/20 0.31
DPP4 P27487 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL28031443 0.97 ACHE (0.36) ACHEGPR3DAORAPGEF4HDAC1
Hydrochloric Acid SCHEMBL29178225 0.97 ACHE (0.36) ACHEGPR3DAORAPGEF4HDAC1
Methyl Alcohol SCHEMBL28273171 0.94 DAO (0.36) ACHEGPR3DAORAPGEF4HDAC1
SCHEMBL261036 0.93 ACHE (0.42) ACHEGPR3DAORAPGEF4HDAC1
SCHEMBL10147311 0.89 ACHE (0.40) ACHEGPR3DAORAPGEF4HDAC1
SCHEMBL30166047 0.86 CYP3A4 (0.40) ACHEGPR3DAORAPGEF4HDAC1
SCHEMBL1057045 0.86 CYP3A4 (0.40) ACHEGPR3DAORAPGEF4HDAC1
SCHEMBL18867947 0.86 CYP3A4 (0.40) ACHEGPR3DAORAPGEF4HDAC1
SCHEMBL5616902 0.85 ACHE (0.42) ACHERAPGEF4HDAC1HDAC6PTGS2
SCHEMBL30867032 0.85 ACHE (0.42) ACHERAPGEF4HDAC1HDAC6PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 528 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260058204-A1 ELECTROLYTE COMPOSITION FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY CONTAINING THE SAME HYUNDAI MOTOR CO LTD (KR) 2026-02-26 US claimed
CN-119804769-A Sampling detection device and method based on preparation of 2,4, 5-trifluoro phenylacetic acid 三明学院 2025-04-11 CN claimed
CN-118791377-B Preparation method of 2,4, 5-trifluoro phenylacetic acid 山东国邦药业有限公司 2025-02-07 CN claimed
CN-118791377-A Preparation method of 2,4, 5-trifluoro phenylacetic acid 山东国邦药业有限公司 2024-10-18 CN claimed
EP-4273147-A1 SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2023-11-08 EP claimed
CN-116924884-A Preparation method of 2,4, 5-trifluoro-benzyl bromide 安庆朗坤药业有限公司 2023-10-24 CN claimed
US-20230131260-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2023-04-27 US claimed
CN-109195966-B Microbiocidal thiazole derivatives 先正达参股股份有限公司 2022-09-16 CN claimed
CN-112851493-B Preparation method of 2,4, 5-trifluoro phenylacetic acid 台州臻挚生物科技有限公司 2022-09-06 CN claimed
WO-2022099439-A1 PREPARATION METHOD FOR 2,4,5-TRIFLUOROPHENYLACETIC ACID 杭州臻挚生物科技有限公司 2022-05-19 WO claimed
EP-3558975-A1 SUBSTITUTED HETEROARYL PYRROLONES AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES Bayer CropScience Aktiengesellschaft (DE) 2019-10-30 EP claimed
EP-3558986-A1 SUBSTITUTED 1,2,4-THIADIAZOLYL PYRROLONES AND 1,2,4-THIADIAZOLYL HYDANTOINES AND SALTS THEREOF AND USE THEREOF AS HERBICIDES Bayer CropScience Aktiengesellschaft (DE) 2019-10-30 EP claimed
CN-110392680-A Substituted azolyl pyrrolidones and azolyl hydantoins and salts thereof and their use as herbicidal active substances 拜耳作物科学股份公司 2019-10-29 CN claimed
CN-110337436-A Substituted 1,2,4- thiadiazolyl group pyrrolones and 1,2,4- thiadiazolyl group hydantoins and its salt and its purposes as herbicide 拜耳作物科学股份公司 2019-10-15 CN claimed
CN-110267950-A Substituted heteroaryl pyrrolones and its salt and its purposes as herbicidal active compounds 拜耳作物科学股份公司 2019-09-20 CN claimed
EP-1267906-A1 LACTAMS AS INHIBITORS OF A-BETA PROTEIN PRODUCTION Bristol-Myers Squibb Pharma Company (US) 2003-01-02 EP claimed
US-6495540-B2 HEXAHYDROAZEPINE-2-ONE DERIVATIVE AS BETA-AMYLOID INHIBITOR BRISTOL - MYERS SQUIBB PHARMA COMPANY 2002-12-17 US claimed
US-20020010172-A1 Lactams as inhibitors of A-beta protein production BRISTOL-MYERS SQUIBB PHARMA COMPANY 2002-01-24 US claimed
WO-2001072324-A1 LACTAMS AS INHIBITORS OF A-BETA PROTEIN PRODUCTION BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2001-10-04 WO claimed
EP-0498724-B1 Esters of 3-(3,3,3-trifluoro-2-chloropropenyl)-2,2-dimethyl-cyclopropanecarboxylic acid, process for their preparation and their use as pesticides ROUSSEL UCLAF (FR) 1996-05-15 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260058204-A1 ELECTROLYTE COMPOSITION FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY CONTAINING THE SAME KCNN2, DYRK1B, SETDB1 ACHE 1953/4885GPR3 3481/4885DAO 1584/4885
US-20020010172-A1 Lactams as inhibitors of A-beta protein production BACE1, APP, APH1A ACHE 62/4885GPR3 4638/4885DAO 211/4885
US-20230131260-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS UNG, TYMP, TYMS ACHE 1932/4885GPR3 3544/4885DAO 252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.