Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624418 | 0.79 | SERPINE1 (0.54) | SERPINE1ALDH1A1RECQLHTR2AHTR1A | |
| SCHEMBL14363101 | 0.69 | SERPINE1 (0.45) | SERPINE1HTR2AHTR1AHTR7 | |
| SCHEMBL7361138 | 0.69 | SERPINE1 (0.44) | SERPINE1ALDH1A1KDM4ESMN1; SMN2SIGMAR1 | |
| SCHEMBL7362526 | 0.66 | SERPINE1 (0.75) | SERPINE1MAPTALDH1A1LMNAHTT | |
| SCHEMBL7362519 | 0.66 | SERPINE1 (0.75) | SERPINE1MAPTALDH1A1LMNAHTT | |
| SCHEMBL7359303 | 0.65 | SERPINE1 (1.00) | SERPINE1HTR2ACYP2D6HTR1AHTR7 | |
| SCHEMBL7363678 | 0.65 | SERPINE1 (0.72) | SERPINE1HTR7 | |
| SCHEMBL7359291 | 0.65 | SERPINE1 (1.00) | SERPINE1HTR2ACYP2D6HTR1AHTR7 | |
| SCHEMBL7363682 | 0.65 | SERPINE1 (0.72) | SERPINE1HTR7 | |
| SCHEMBL7358033 | 0.65 | SERPINE1 (1.00) | SERPINE1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007051314-A1 | CURCUMINOID COMPOUNDS FOR INHIBITING PLASMINOGEN ACTIVATOR INHIBITOR-1 | AMERICAN DIAGNOSTICA INC. (US) | 2007-05-10 | — | — | WO | disclosed |