Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 8/20 | 0.54 |
| ▸ | HTR7 | P34969 | 7/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361138 | 0.88 | SERPINE1 (0.44) | SERPINE1ALDH1A1 | |
| SCHEMBL8238043 | 0.79 | SERPINE1 (0.49) | SERPINE1HTR7HTR1AHTR2AALDH1A1 | |
| SCHEMBL4724956 | 0.78 | ALDH1A1 (0.45) | SERPINE1ALDH1A1 | |
| SCHEMBL8633515 | 0.77 | ALDH1A1 (0.46) | SERPINE1ALDH1A1 | |
| SCHEMBL9724168 | 0.77 | ALDH1A1 (0.44) | SERPINE1ALDH1A1 | |
| SCHEMBL11711430 | 0.75 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL11713091 | 0.75 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL11720811 | 0.75 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL17483811 | 0.75 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL11713052 | 0.75 | ALDH1A1 (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750530-A | PLASMINOGEN ACTIVATOR INHIBITORS | XENOVA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |