Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 20/20 | 0.76 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.56 |
| ▸ | PLAT | P00750 | 2/20 | 0.47 |
| ▸ | KLK1 | P06870 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1197010 | 0.94 | F11 (0.85) | F11KLKB1PLATKLK1F10 | |
| SCHEMBL12011711 | 0.94 | F11 (0.70) | F11KLKB1PLATKLK1 | |
| SCHEMBL8241339 | 0.92 | F11 (0.76) | F11KLKB1PLATKLK1F10 | |
| SCHEMBL1197442 | 0.89 | F11 (0.89) | F11KLKB1PLATKLK1F10 | |
| SCHEMBL1197448 | 0.89 | F11 (0.89) | F11KLKB1PLATKLK1F10 | |
| SCHEMBL12011714 | 0.89 | F11 (0.74) | F11KLKB1PLATKLK1 | |
| SCHEMBL8238423 | 0.88 | F11 (0.70) | F11KLKB1PLATKLK1F10 | |
| SCHEMBL1197447 | 0.88 | F11 (0.87) | F11KLKB1PLATKLK1F10 | |
| SCHEMBL1197449 | 0.88 | F11 (0.87) | F11KLKB1PLATKLK1F10 | |
| SCHEMBL1196504 | 0.87 | F11 (0.86) | F11KLKB1PLATKLK1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007070826-A1 | ARYLPROPIONAMIDE, ARYLACRYLAMIDE, ARYLPROPYNAMIDE, OR ARYLMETHYLUREA ANALOGS AS FACTOR XIA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-06-21 | — | — | WO | disclosed |