Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 18/20 | 0.50 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL779713 | 1.00 | ADRA1A (0.50) | ADRA1ANISCHADRA2AADRA1DADRA1B | |
| SCHEMBL779724 | 1.00 | ADRA1A (0.50) | ADRA1ANISCHADRA2AADRA1DADRA1B | |
| SCHEMBL768928 | 1.00 | ADRA1A (0.50) | ADRA1ANISCHADRA2AADRA1DADRA1B | |
| SCHEMBL768901 | 0.75 | ADRA1A (0.58) | ADRA1ANISCHADRA2AADRA1DADRA1B | |
| SCHEMBL769246 | 0.75 | ADRA1A (0.48) | ADRA1ANISCHADRA2AADRA1DADRA1B | |
| SCHEMBL769091 | 0.70 | NISCH (0.55) | ADRA1ANISCHADRA2AADRA1DADRA1B | |
| SCHEMBL787224 | 0.70 | NISCH (0.55) | ADRA1ANISCHADRA2AADRA1DADRA1B | |
| SCHEMBL779851 | 0.70 | NISCH (0.55) | ADRA1ANISCHADRA2AADRA1DADRA1B | |
| SCHEMBL787051 | 0.70 | NISCH (0.55) | ADRA1ANISCHADRA2AADRA1DADRA1B | |
| SCHEMBL8240928 | 0.70 | NISCH (0.55) | ADRA1ANISCHADRA2AADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007085558-A1 | USE OF 2-IMIDAZOLES FOR THE TREATMENT OF CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-08-02 | — | — | WO | disclosed |