Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 11/20 | 0.61 |
| ▸ | GRM4 | Q14833 | 11/20 | 0.61 |
| ▸ | GRM6 | O15303 | 4/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10000466 | 0.93 | GRM8 (0.56) | GRM8GRM4GRM6HDAC1HDAC2 | |
| SCHEMBL13774905 | 0.85 | GRM8 (0.52) | GRM8GRM4GRM6HDAC1HDAC2 | |
| SCHEMBL346779 | 0.84 | GRM8 (0.54) | GRM8GRM4GRM6HDAC1HDAC2 | |
| SCHEMBL346780 | 0.84 | GRM8 (0.54) | GRM8GRM4GRM6HDAC1HDAC2 | |
| SCHEMBL13774966 | 0.83 | GRM8 (0.53) | GRM8GRM4GRM6HDAC1HDAC2 | |
| SCHEMBL13774896 | 0.83 | GRM8 (0.53) | GRM8GRM4GRM6HDAC1HDAC2 | |
| SCHEMBL8238396 | 0.79 | GRM8 (0.56) | GRM8GRM4GRM6 | |
| SCHEMBL4085127 | 0.79 | GRM8 (0.58) | GRM8GRM4GRM6 | |
| SCHEMBL13774898 | 0.79 | GRM8 (0.56) | GRM8GRM4HDAC1HDAC2CTSL | |
| SCHEMBL8241361 | 0.79 | GRM8 (0.56) | GRM8GRM4HDAC1HDAC2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007052169-A2 | HYPOPHOSPHOROUS ACID DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-05-10 | — | — | WO | disclosed |