Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.56 |
| ▸ | FAP | Q12884 | 6/20 | 0.56 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.56 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.56 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.56 |
| ▸ | KDM1A | O60341 | 12/20 | 0.55 |
| ▸ | KDM1B | Q8NB78 | 7/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15906353 | 1.00 | DPP4 (0.56) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL15072097 | 0.86 | KDM1A (0.70) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL8231317 | 0.82 | KDM1A (0.74) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL8272637 | 0.78 | KDM1A (0.47) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL12354272 | 0.78 | KDM1A (0.47) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL4562700 | 0.78 | KDM1A (0.47) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL14845909 | 0.73 | DPP4 (1.00) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL8271959 | 0.73 | DPP4 (1.00) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL13937990 | 0.73 | DPP4 (1.00) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL8237697 | 0.72 | DPP4 (0.75) | DPP4FAPDPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007087231-A2 | AMINOCYCLOHEXANES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | MERCK & CO., INC. (US) | 2007-08-02 | — | — | WO | disclosed |