Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 18/20 | 0.70 |
| ▸ | KDM1B | Q8NB78 | 11/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.70 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | FAP | Q12884 | 1/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15906353 | 0.86 | DPP4 (0.56) | KDM1AKDM1BKCNH2DPP4FAP | |
| SCHEMBL8239356 | 0.86 | DPP4 (0.56) | KDM1AKDM1BKCNH2DPP4FAP | |
| SCHEMBL12354272 | 0.79 | KDM1A (0.47) | KDM1AKDM1BKCNH2DPP4FAP | |
| SCHEMBL8272637 | 0.79 | KDM1A (0.47) | KDM1AKDM1BKCNH2DPP4FAP | |
| SCHEMBL4562700 | 0.79 | KDM1A (0.47) | KDM1AKDM1BKCNH2DPP4FAP | |
| SCHEMBL29941500 | 0.77 | CHRNB2 (0.47) | KDM1AKDM1BKCNH2DPP4FAP | |
| SCHEMBL470620 | 0.77 | CHRNB2 (0.47) | KDM1AKDM1BKCNH2DPP4FAP | |
| SCHEMBL15597453 | 0.76 | KDM1A (0.71) | KDM1AKDM1BKCNH2 | |
| SCHEMBL8226525 | 0.70 | DPP4 (0.50) | KCNH2DPP4FAPDPP8DPP7 | |
| SCHEMBL25004852 | 0.70 | KDM1A (0.39) | KDM1AKDM1BKCNH2DPP4FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130165696-A1 | NOVEL PROCESSES FOR THE PREPARATION OF PHENYLCYCLOPROPYLAMINE DERIVATIVES AND USE THEREOF FOR PREPARING TICAGRELOR | ACTAVIS GROUP PTC EHF (IS) | 2013-06-27 | — | — | US | disclosed |
| US-20130165696-A1 | NOVEL PROCESSES FOR THE PREPARATION OF PHENYLCYCLOPROPYLAMINE DERIVATIVES AND USE THEREOF FOR PREPARING TICAGRELOR | ACTAVIS GROUP PTC EHF (IS) | 2013-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165696-A1 | NOVEL PROCESSES FOR THE PREPARATION OF PHENYLCYCLOPROPYLAMINE DERIVATIVES AND USE THEREOF FOR PREPARING TICAGRELOR | THPO, P2RY4, TBXA2R | KDM1A 3290/4885KDM1B 3834/4885KCNH2 2235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.