Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP6 | P51161 | 1/20 | 0.72 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | TYMS | P04818 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MASP2 | O00187 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL393703 | 0.84 | FABP6 (1.00) | FABP6PLAUHTR3EHTR3BHTR3A | |
| SCHEMBL14278 | 0.84 | FABP6 (0.59) | FABP6PLAUHTR3EHTR3BHTR3A | |
| Bromide SCHEMBL23295657 | 0.82 | FABP6 (0.96) | FABP6PLAUHTR3EHTR3BHTR3A | |
| Water SCHEMBL10985661 | 0.82 | FABP6 (0.96) | FABP6PLAUHTR3EHTR3BHTR3A | |
| SCHEMBL12819467 | 0.81 | MAPT (0.51) | FABP6TYMSMEN1KMT2AMAPT | |
| SCHEMBL14502996 | 0.78 | MEN1 (0.43) | FABP6MEN1KMT2AMAPTATM | |
| SCHEMBL14247949 | 0.78 | FABP6 (0.72) | FABP6PLAUHTR3EHTR3BHTR3A | |
| SCHEMBL5924157 | 0.78 | HTR3E (0.53) | FABP6PLAUHTR3EHTR3BHTR3A | |
| SCHEMBL5680925 | 0.78 | FABP6 (0.72) | FABP6PLAUHTR3EHTR3BHTR3A | |
| SCHEMBL13619367 | 0.77 | FABP6 (0.51) | FABP6PLAUHTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076431-A1 | MACROCYCLIC FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-07-05 | — | — | WO | disclosed |