Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4Z1 | Q86W10 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.35 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | USP14 | P54578 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8234864 | 0.95 | CYP4Z1 (0.39) | CYP4Z1TSHRCYP4F11CYP4F12CYP4F2 | |
| SCHEMBL2295671 | 0.94 | CYP4Z1 (0.39) | CYP4Z1TSHRCYP4F11CYP4F12CYP4F2 | |
| SCHEMBL2289975 | 0.92 | CYP4Z1 (0.37) | CYP4Z1TSHRCYP4F11CYP4F12CYP4F2 | |
| SCHEMBL8233563 | 0.92 | TSHR (0.36) | CYP4Z1TSHRCYP4F11CYP4F12CYP4F2 | |
| SCHEMBL2291678 | 0.88 | TSHR (0.39) | CYP4Z1TSHRCYP4F11CYP4F12CYP4F2 | |
| SCHEMBL2289618 | 0.85 | TSHR (0.37) | CYP4Z1TSHRCYP4F11CYP4F12CYP4F2 | |
| SCHEMBL8240083 | 0.77 | PTPRB (0.37) | TSHRCYP4F2CYP4A11TDP1KDM4E | |
| SCHEMBL8918786 | 0.74 | MEN1 (0.42) | TSHRCYP4F2CYP4A11USP14MAPK1 | |
| SCHEMBL8466268 | 0.73 | CYP4Z1 (0.54) | CYP4Z1TSHRCYP4F11CYP4F12CYP4F2 | |
| SCHEMBL2294364 | 0.72 | PTPRB (0.40) | TSHRCYP4F2CYP4A11TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007045370-A1 | TETRAZOL DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CARDIOVASCULAR DISEASES | BAYER HEALTHCARE AG (DE) | 2007-04-26 | — | — | WO | disclosed |