SCHEMBL823968

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28997262	0.82	MAPT (0.56)	ALDH1A1MAPTNPC1MEN1KMT2A
	SCHEMBL22743387	0.82	GAA (0.60)	ALDH1A1MAPTNPC1POLBMEN1
	SCHEMBL30225952	0.82	MEN1 (0.66)	HDAC4HDAC3HDAC1HDAC7HDAC2
	SCHEMBL30226098	0.82	MAPT (0.56)	ALDH1A1MAPTNPC1MEN1KMT2A
	SCHEMBL28997258	0.82	MEN1 (0.66)	HDAC4HDAC3HDAC1HDAC7HDAC2
	SCHEMBL30544715	0.82	HDAC3 (0.62)	HDAC4HDAC3HDAC1HDAC7HDAC2
	SCHEMBL29054673	0.82	HDAC3 (0.62)	HDAC4HDAC3HDAC1HDAC7HDAC2
	SCHEMBL13363465	0.81	HDAC1 (0.91)	HDAC4HDAC3HDAC1HDAC7HDAC2
	SCHEMBL2577548	0.80	NAMPT (0.62)	HDAC4HDAC3HDAC1HDAC7HDAC2
	SCHEMBL11597168	0.80	HDAC3 (0.72)	HDAC4HDAC3HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.