Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314720 | 0.86 | HDAC1 (0.63) | HDAC1HDAC2KCNH2HDAC3 | |
| SCHEMBL3656182 | 0.81 | HDAC1 (0.63) | HDAC1HDAC2KCNH2HDAC3 | |
| SCHEMBL3651661 | 0.81 | HDAC1 (0.55) | HDAC1HDAC2LMNAKCNH2KMT2A | |
| SCHEMBL2077347 | 0.79 | HDAC1 (0.64) | HDAC1KCNH2HDAC3 | |
| SCHEMBL3621805 | 0.73 | HDAC1 (0.67) | HDAC1HDAC2KCNH2 | |
| SCHEMBL5317952 | 0.72 | HDAC1 (0.63) | HDAC1HDAC2KCNH2HDAC3 | |
| SCHEMBL8236120 | 0.72 | HDAC1 (0.48) | HDAC1HDAC2KCNH2 | |
| SCHEMBL4259246 | 0.70 | KMT2A (0.49) | LMNAKMT2A | |
| SCHEMBL4276208 | 0.69 | KMT2A (0.63) | LMNAPOLBKMT2ACYP2C9 | |
| SCHEMBL12841911 | 0.68 | HDAC1 (0.54) | HDAC1KCNH2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071961-A1 | BENZAMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-06-28 | — | — | WO | disclosed |