Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.67 |
| ▸ | ADORA1 | P30542 | 14/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3873992 | 0.81 | ADORA2A (1.00) | ADORA2AADORA1ADORA3 | |
| SCHEMBL3869311 | 0.80 | ADORA2A (1.00) | ADORA2AADORA1ADORA3 | |
| SCHEMBL3869262 | 0.77 | ADORA2A (1.00) | ADORA2AADORA1ADORA3 | |
| SCHEMBL8245876 | 0.73 | ADORA2A (1.00) | ADORA2AADORA1ADORA3 | |
| SCHEMBL3869221 | 0.71 | ADORA2A (1.00) | ADORA2AADORA1 | |
| SCHEMBL3869368 | 0.69 | ADORA2A (0.79) | ADORA2AADORA1ADORA3 | |
| SCHEMBL3878528 | 0.69 | ADORA2A (1.00) | ADORA2AADORA1 | |
| SCHEMBL8247763 | 0.69 | ADORA2A (0.73) | ADORA2AADORA1ADORA3 | |
| SCHEMBL13936074 | 0.68 | ADORA2A (0.81) | ADORA2AADORA1ADORA3 | |
| SCHEMBL16440392 | 0.67 | ADORA2A (0.73) | ADORA2AADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007022415-A2 | SUBSTITUTED 2-AMINOTHIAZOLES FOR TREATING NEURODEGENERATIVE DISEASES | PHARMACOPEIA, INC. (US) | 2007-02-22 | — | — | WO | disclosed |