Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 1/20 | 0.45 |
| ▸ | RORB | Q92753 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5049013 | 0.90 | IL2 (0.54) | IL2RORBKMT2AALDH1A1MEN1 | |
| SCHEMBL8237663 | 0.81 | IL2 (0.46) | IL2RORBKMT2AALDH1A1MEN1 | |
| SCHEMBL8239548 | 0.81 | IL2 (0.46) | IL2RORBKMT2AALDH1A1MEN1 | |
| SCHEMBL5049039 | 0.81 | IL2 (0.54) | IL2RORBKMT2AALDH1A1MEN1 | |
| SCHEMBL8237636 | 0.81 | IL2 (0.46) | IL2RORBKMT2AALDH1A1MEN1 | |
| SCHEMBL5049038 | 0.80 | IL2 (0.55) | IL2RORBKMT2AALDH1A1MEN1 | |
| SCHEMBL5049909 | 0.78 | IL2 (0.58) | IL2RORBKMT2AALDH1A1MEN1 | |
| SCHEMBL8239902 | 0.78 | IL2 (0.41) | IL2RORBKMT2AALDH1A1MEN1 | |
| SCHEMBL5049766 | 0.77 | IL2 (0.57) | IL2RORBKMT2AALDH1A1MEN1 | |
| SCHEMBL5245746 | 0.77 | IL2 (0.57) | IL2RORBKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007087427-A2 | THIAZOLE AND THIADIAZOLE COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2007-08-02 | — | — | WO | disclosed |