Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8239980 | 0.88 | IKBKB (0.43) | KDM4EALDH1A1IKBKBCHUKLIMK1 | |
| SCHEMBL4533878 | 0.84 | KDM4E (0.48) | KDM4EALDH1A1MAPTHPGDTP53 | |
| SCHEMBL5648903 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL13605637 | 0.84 | KDM4E (0.52) | KDM4EALDH1A1IKBKBCHUKLIMK1 | |
| SCHEMBL5516014 | 0.83 | LIMK1 (0.66) | KDM4EALDH1A1IKBKBCHUKLIMK1 | |
| SCHEMBL13605638 | 0.82 | TP53 (0.50) | KDM4EALDH1A1MAPTTP53 | |
| SCHEMBL4528888 | 0.79 | KDM4E (0.45) | KDM4EALDH1A1IKBKBCHUKLIMK1 | |
| SCHEMBL4528867 | 0.76 | KDM4E (0.47) | KDM4EMAPTHPGDTP53THRB | |
| SCHEMBL13605639 | 0.75 | PADI4 (0.49) | KDM4EALDH1A1MAPT | |
| SCHEMBL4518456 | 0.74 | MAPT (0.43) | KDM4EALDH1A1IKBKBCHUKLIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007072090-A1 | THIENOPYRIDINE DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | RICHTER GEDEON NYRT. (HU) | 2007-06-28 | — | — | WO | disclosed |