Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4225103 | 0.99 | DPP4 (0.53) | DPP4KCNH2ALDH1A1L3MBTL1TSHR | |
| SCHEMBL13780196 | 0.89 | DPP4 (0.52) | DPP4KCNH2ALDH1A1L3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL4225897 | 0.88 | DPP4 (0.52) | DPP4KCNH2ALDH1A1L3MBTL1TSHR | |
| SCHEMBL8240070 | 0.84 | DPP4 (0.61) | DPP4KCNH2FAP | |
| Hydrochloric Acid SCHEMBL4224919 | 0.83 | DPP4 (0.61) | DPP4KCNH2FAP | |
| SCHEMBL8230984 | 0.82 | DPP4 (0.69) | DPP4KCNH2FAP | |
| SCHEMBL8230451 | 0.82 | DPP4 (0.62) | DPP4KCNH2ALDH1A1L3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL4220187 | 0.81 | DPP4 (0.68) | DPP4KCNH2FAP | |
| SCHEMBL4230360 | 0.80 | DPP4 (0.45) | DPP4KCNH2ALDH1A1TSHRLMNA | |
| SCHEMBL8237262 | 0.77 | DPP4 (0.68) | DPP4KCNH2L3MBTL1FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090192129-A1 | BICYCLIC PYRROLE DERIVATIVES | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-07-30 | — | — | US | disclosed |
| US-20090192129-A1 | BICYCLIC PYRROLE DERIVATIVES | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-07-30 | — | — | US | disclosed |
| US-20090192138-A1 | COMPOUNDS | BAESCHLIN DANIEL KASPAR | 2009-07-30 | — | — | US | disclosed |
| US-20090192138-A1 | COMPOUNDS | BAESCHLIN DANIEL KASPAR | 2009-07-30 | — | — | US | disclosed |
| WO-2007071738-A1 | CONDENSED HETEROCYCLIC COMPOUNDS USEFUL AS DPP-IV INHIBITORS | NOVARTIS AG (CH) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192129-A1 | BICYCLIC PYRROLE DERIVATIVES | DPP4, DPP7, DPP3 | DPP4 1/4885KCNH2 1787/4885ALDH1A1 22/4885 |
| US-20090192138-A1 | COMPOUNDS | DPP4, DPP3, DPP8 | DPP4 1/4885KCNH2 1859/4885ALDH1A1 363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.