SCHEMBL824059

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL823960	0.90	AIMP2 (0.47)	JAK2JAK3FLT3PIK3CGPIK3CA
	SCHEMBL824072	0.84	PIK3CA (0.44)	MAPTJAK2JAK3FLT3PIK3CG
	SCHEMBL19766407	0.77	PLK1 (0.45)	JAK2PIK3CGPIK3CAPIK3CBCDK4
	SCHEMBL12352801	0.75	PIK3CG (0.47)	JAK2JAK3PIK3CGPIK3CAPIK3CB
	SCHEMBL823940	0.73	SYK (0.39)	JAK2JAK3FLT3PIK3CGPIK3CA
	SCHEMBL11955402	0.73	ABL1 (0.47)	JAK2JAK3PIK3CGPIK3CAPIK3CB
	SCHEMBL1098726	0.72	ABL1 (0.46)	JAK2PIK3CGPIK3CAPIK3CBAIMP2
	SCHEMBL3045105	0.72	CDK5 (0.58)	JAK2FLT3PIK3CGPIK3CAPIK3CB
	SCHEMBL14531627	0.71	PLK1 (0.52)	JAK2JAK3PIK3CGCDK4CDK2
	SCHEMBL4813575	0.71	EGFR (0.37)	MAPTEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.