Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KRAS | P01116 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65671 | 0.84 | F10 (0.44) | KMOHRH3KRASMAPTF10 | |
| SCHEMBL56764 | 0.84 | F10 (0.44) | MEN1KMT2AALDH1A1KMOHRH3 | |
| SCHEMBL57175 | 0.80 | TACR1 (0.43) | KMOHRH3KRASMAPTF10 | |
| SCHEMBL57307 | 0.79 | HRH3 (0.48) | KMT2AKMOHRH3KRASMAPT | |
| SCHEMBL66257 | 0.77 | F2 (0.43) | KMT2APOLBKMOHRH3SMN1; SMN2 | |
| SCHEMBL13980991 | 0.77 | KMO (0.58) | LMNAKMOSMN1; SMN2KRASMAPT | |
| SCHEMBL66061 | 0.76 | HRH3 (0.41) | KMOHRH3KRASMAPTF10 | |
| SCHEMBL10203773 | 0.76 | KMO (0.57) | LMNAKMOSMN1; SMN2KRASMAPT | |
| SCHEMBL1576323 | 0.76 | KMO (0.78) | LMNAKMOHTR2AHTR2COXER1 | |
| SCHEMBL11947275 | 0.74 | KMO (0.44) | MEN1KMT2AALDH1A1HPGDKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007050522-A1 | DERIVATIVES FOR MODULATION OF ION CHANNELS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2007-05-03 | — | — | WO | disclosed |