Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ECE1 | P42892 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19477882 | 0.81 | POLB (0.47) | TSHRMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL23177699 | 0.81 | POLB (0.47) | TSHRMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL12017878 | 0.77 | TSHR (0.50) | TSHRCA12CA14CA7CA9 | |
| SCHEMBL22183413 | 0.77 | MEN1 (0.36) | TSHRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL2149827 | 0.74 | TSHR (0.46) | TSHRCA12CA14CA7CA9 | |
| SCHEMBL25328393 | 0.74 | TSHR (0.46) | TSHRCA12CA14CA7CA9 | |
| SCHEMBL18704629 | 0.74 | ALDH1A1 (0.47) | TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL19477772 | 0.73 | MEN1 (0.42) | MEN1KMT2APOLB | |
| SCHEMBL12019233 | 0.73 | TSHR (0.44) | TSHRCA12CA14CA7CA9 | |
| SCHEMBL20813493 | 0.71 | TSHR (0.43) | TSHRCA12CA14CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007049803-A1 | NEW CYCLIC PEPTIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2007-05-03 | — | — | WO | disclosed |