Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 3/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8253773 | 0.86 | ELANE (0.41) | STAT6ELANE | |
| SCHEMBL25906663 | 0.86 | ELANE (0.41) | STAT6ELANE | |
| SCHEMBL14302404 | 0.85 | STAT6 (0.39) | STAT6 | |
| SCHEMBL8250711 | 0.83 | DPP4 (0.39) | STAT6ELANEDPP4DPP8 | |
| SCHEMBL21696763 | 0.83 | STAT6 (0.43) | STAT6ELANEHCRTR2DPP4DPP8 | |
| SCHEMBL25885362 | 0.83 | STAT6 (0.43) | STAT6ELANEHCRTR2DPP4DPP8 | |
| SCHEMBL23959050 | 0.82 | DPP4 (0.37) | STAT6DPP4DPP8DPP9 | |
| SCHEMBL26749959 | 0.81 | STAT6 (0.38) | STAT6ELANEDPP4DPP8DPP9 | |
| SCHEMBL8145204 | 0.81 | ELANE (0.43) | STAT6ELANE | |
| SCHEMBL22525831 | 0.80 | DPP4 (0.39) | STAT6DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006130686-A2 | HCV PROTEASE INHIBITORS IN COMBINATION WITH FOOD | SCHERING CORPORATION (US) | 2006-12-07 | — | — | WO | disclosed |
| WO-2006130688-A2 | COMPOUNDS FOR INHIBITING CATHEPSIN ACTIVITY | SCHERING CORPORATION (US) | 2006-12-07 | — | — | WO | disclosed |