Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.59 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8237955 | 0.94 | EGLN1 (0.64) | EGLN1EGLN3MEN1KMT2AL3MBTL1 | |
| SCHEMBL8248114 | 0.88 | EGLN1 (0.76) | EGLN1EGLN3MEN1KMT2AL3MBTL1 | |
| SCHEMBL8245606 | 0.84 | HIF1A (0.56) | EGLN1EGLN3L3MBTL1POLBHIF1A | |
| SCHEMBL8248316 | 0.83 | HIF1A (0.55) | EGLN1EGLN3L3MBTL1POLBHIF1A | |
| SCHEMBL8247341 | 0.82 | EGLN1 (0.67) | EGLN1EGLN3L3MBTL1HIF1AKDM4E | |
| SCHEMBL8249796 | 0.82 | HIF1A (0.58) | EGLN1EGLN3L3MBTL1HIF1A | |
| SCHEMBL8238787 | 0.82 | EGLN3 (0.59) | EGLN1EGLN3L3MBTL1HIF1A | |
| SCHEMBL8248071 | 0.82 | HIF1A (0.56) | EGLN1EGLN3MEN1KMT2AL3MBTL1 | |
| SCHEMBL5311732 | 0.82 | EGLN3 (0.69) | EGLN1EGLN3L3MBTL1HIF1A | |
| SCHEMBL5308363 | 0.82 | EGLN1 (0.63) | EGLN1EGLN3L3MBTL1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |