Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.52 |
| ▸ | HPGD | P15428 | 9/20 | 0.47 |
| ▸ | GLA | P06280 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 3/20 | 0.41 |
| ▸ | CASP7 | P55210 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4708970 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL4712639 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL4711997 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL8245291 | 0.75 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL4711956 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL4708939 | 0.72 | KDM4E (0.53) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL4709454 | 0.71 | RXFP1 (0.54) | ALDH1A1KDM4EHPGDMAPTCYP1A2 | |
| SCHEMBL4711017 | 0.71 | KDM4E (0.95) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL8244489 | 0.71 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL1095581 | 0.65 | ELANE (0.55) | KDM4ECYP1A2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007045876-A1 | CHROMENONES AND THEIR USE AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2007-04-26 | — | — | WO | disclosed |