Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 2/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3484871 | 0.96 | KDM4E (0.47) | KDM4EMAPTSMN1; SMN2LMNAATM | |
| SCHEMBL3484872 | 0.96 | KDM4E (0.47) | KDM4EMAPTSMN1; SMN2LMNAATM | |
| SCHEMBL8242476 | 0.93 | PPARG (0.40) | KDM4EMAPTSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL8241651 | 0.92 | PPARG (0.41) | KDM4EMAPTKMT2AALDH1A1CRHBP | |
| SCHEMBL8241509 | 0.91 | TP53 (0.41) | MAPTKMT2AALDH1A1PPARGMEN1 | |
| SCHEMBL8243864 | 0.90 | PTGER1 (0.49) | KDM4EMAPTSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL8243984 | 0.90 | PDE4A (0.45) | KDM4EMAPTKMT2AALDH1A1CRHBP | |
| SCHEMBL8244612 | 0.90 | RXRA (0.44) | KDM4EMAPTLMNAKMT2AALDH1A1 | |
| SCHEMBL3485369 | 0.89 | KMT2A (0.43) | KDM4EMAPTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL3485367 | 0.89 | KMT2A (0.43) | KDM4EMAPTSMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007045433-A1 | DICARBOXYLIC ACID DERIVATIVES AND THEIR USE | BAYER HEALTHCARE AG (DE) | 2007-04-26 | — | — | WO | disclosed |