Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5243822 | 0.92 | PDE5A (0.80) | PDE5AKCNH2 | |
| SCHEMBL5244793 | 0.88 | PDE5A (1.00) | PDE5AKCNH2 | |
| SCHEMBL13810209 | 0.88 | PDE5A (0.71) | PDE5AKCNH2 | |
| SCHEMBL8261391 | 0.88 | PDE5A (0.86) | PDE5AKCNH2 | |
| SCHEMBL12768920 | 0.86 | PDE5A (0.77) | PDE5AKCNH2 | |
| SCHEMBL8236337 | 0.85 | PDE5A (0.76) | PDE5AKCNH2 | |
| SCHEMBL8300021 | 0.85 | PDE5A (0.79) | PDE5AKCNH2 | |
| SCHEMBL8243114 | 0.85 | PDE5A (1.00) | PDE5AKCNH2 | |
| SCHEMBL5426271 | 0.85 | PDE5A (0.76) | PDE5AKCNH2 | |
| SCHEMBL12840899 | 0.83 | PDE5A (0.78) | PDE5AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007054778-A1 | PYRAZOLO[4,3-D]PYRIMIDIN-5-YL)DERIVATIVE USED AS PDE5 INHIBITORS | PFIZER PRODUCTS INC. (US) | 2007-05-18 | — | — | WO | disclosed |