Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8261391 | 0.92 | PDE5A (0.86) | PDE5AKCNH2 | |
| SCHEMBL5247246 | 0.90 | PDE5A (0.78) | PDE5AKCNH2 | |
| SCHEMBL5246095 | 0.90 | PDE5A (0.78) | PDE5AKCNH2 | |
| SCHEMBL5248592 | 0.89 | PDE5A (0.67) | PDE5AKCNH2 | |
| SCHEMBL5246377 | 0.89 | PDE5A (0.67) | PDE5AKCNH2 | |
| SCHEMBL8243114 | 0.88 | PDE5A (1.00) | PDE5AKCNH2 | |
| SCHEMBL5247530 | 0.88 | PDE5A (0.72) | PDE5AKCNH2 | |
| SCHEMBL5245905 | 0.88 | PDE5A (0.72) | PDE5AKCNH2 | |
| SCHEMBL8240743 | 0.87 | PDE5A (0.77) | PDE5AKCNH2 | |
| SCHEMBL8245307 | 0.85 | PDE5A (0.79) | PDE5AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096810-A1 | 5,7-DIAMINOPYRAZOLO`4,3-D!PYRIMIDINES USEFUL IN THE TREATMENT OF HYPERTENSION | PFIZER LIMITED (GB) | 2004-11-11 | — | — | WO | disclosed |