SCHEMBL824561

SCHEMBL824561

[C-]#[N+]c1cnn(-c2ccncn2)c1/N=N/c1c(C)nn(-c2ccccn2)c1N

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.49
RAB9A P51151 7/20 0.39
NPC1 O15118 6/20 0.39
SMN1; SMN2 Q16637 6/20 0.39
HPGD P15428 5/20 0.37
L3MBTL1 Q9Y468 3/20 0.37
ALDH1A1 P00352 3/20 0.37
HTT P42858 3/20 0.37
TP53 P04637 2/20 0.37
KDM4E B2RXH2 2/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 4/20 0.36
KMT2A Q03164 4/20 0.34
MAPK1 P28482 3/20 0.34
MEN1 O00255 3/20 0.34
CYP17A1 P05093 2/20 0.34
ALOX12 P18054 1/20 0.34
SPR P35270 1/20 0.34
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL824593 0.93 MAPT (0.56) MAPTRAB9ANPC1SMN1; SMN2HPGD
SCHEMBL824873 0.89 MAPT (0.49) MAPTRAB9ANPC1SMN1; SMN2HPGD
SCHEMBL824570 0.89 MAPT (0.50) MAPTRAB9ANPC1SMN1; SMN2HPGD
SCHEMBL824869 0.89 MAPT (0.53) MAPTRAB9ANPC1SMN1; SMN2HPGD
SCHEMBL824630 0.87 MAPT (0.49) MAPTRAB9ANPC1SMN1; SMN2HPGD
SCHEMBL10194370 0.85 MAPT (0.43) MAPTRAB9ANPC1SMN1; SMN2HPGD
SCHEMBL10194371 0.83 MAPT (0.45) MAPTRAB9ANPC1SMN1; SMN2HPGD
SCHEMBL10194374 0.83 MAPT (0.45) MAPTRAB9ANPC1SMN1; SMN2HPGD
SCHEMBL824572 0.80 MAPT (0.39) MAPTRAB9ANPC1SMN1; SMN2HPGD
SCHEMBL824632 0.80 MAPT (0.41) MAPTRAB9ANPC1SMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142519-B2 Azo pigment, and pigment dispersion, coloring composition and ink composition for inkjet recording containing the same FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
US-20100258036-A1 AZO PIGMENT, AND PIGMENT DISPERSION, COLORING COMPOSITION AND INK COMPOSITION FOR INKJET RECORDING CONTAINING THE SAME FUJIFILM CORPORATION (JP) 2010-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100258036-A1 AZO PIGMENT, AND PIGMENT DISPERSION, COLORING COMPOSITION AND INK COMPOSITION FOR INKJET RECORDING CONTAINING THE SAME WNT1, CYP1A1, CYP1B1 MAPT 372/4885RAB9A 910/4885NPC1 2980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.