Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | GAA | P10253 | 4/20 | 1.00 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | PARP1 | P09874 | 2/20 | 0.55 |
| ▸ | CDC25B | P30305 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | SAE1 | Q9UBE0 | 3/20 | 0.54 |
| ▸ | UBA2 | Q9UBT2 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | THRB | P10828 | 3/20 | 0.54 |
| ▸ | UBE2I | P63279 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | APAF1 | O14727 | 5/20 | 0.51 |
| ▸ | CASP3 | P42574 | 4/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29488099 | 1.00 | KDM4E (1.00) | KDM4EGAALOXL2ALDH1A1PARP1 | |
| SCHEMBL16591247 | 0.79 | KDM4E (0.65) | KDM4EGAALOXL2ALDH1A1PARP1 | |
| SCHEMBL24460075 | 0.78 | KDM4E (0.64) | KDM4EGAAALDH1A1PARP1HPGD | |
| SCHEMBL824579 | 0.78 | KDM4E (0.63) | KDM4EGAAALDH1A1PARP1CDC25B | |
| SCHEMBL824649 | 0.78 | KDM4E (0.63) | KDM4EGAAALDH1A1PARP1CDC25B | |
| SCHEMBL1720643 | 0.76 | LOXL2 (0.68) | KDM4EGAALOXL2ALDH1A1PARP1 | |
| SCHEMBL150458 | 0.75 | KDM4E (0.60) | KDM4EGAALOXL2ALDH1A1PARP1 | |
| SCHEMBL1719778 | 0.75 | LOXL2 (0.61) | KDM4EGAALOXL2ALDH1A1PARP1 | |
| SCHEMBL1687342 | 0.75 | KDM4E (0.60) | KDM4EGAALOXL2ALDH1A1PARP1 | |
| SCHEMBL1818129 | 0.75 | KDM4E (0.60) | KDM4EGAALOXL2ALDH1A1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 313 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12338486-B2 | Single-stranded break detection in double-stranded DNA | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-06-24 | — | — | US | claimed |
| EP-3781711-B1 | SINGLE-STRANDED BREAK DETECTION IN DOUBLE-STRANDED DNA | MASSACHUSETTS INST TECHNOLOGY (US) | 2024-11-20 | — | — | EP | claimed |
| CN-114457145-B | Linkers, constructs, methods and uses for characterizing target polynucleotide sequencing | 成都齐碳科技有限公司 | 2023-08-11 | — | — | CN | claimed |
| WO-2023143247-A1 | LINKER FOR CHARACTERIZING SEQUENCING OF TARGET POLYNUCLEOTIDE, CONSTRUCT, METHOD, AND USE | 成都齐碳科技有限公司 | 2023-08-03 | — | — | WO | claimed |
| US-11505827-B2 | Systems and methods for determining genetic data | Roche Sequencing Solutions, Inc. (US) | 2022-11-22 | — | — | US | claimed |
| CN-114457145-A | Linkers, constructs, methods, and uses for characterizing sequencing of target polynucleotides | 成都齐碳科技有限公司 | 2022-05-10 | — | — | CN | claimed |
| US-20210071240-A1 | SINGLE-STRANDED BREAK DETECTION IN DOUBLE-STRANDED DNA | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-03-11 | — | — | US | claimed |
| EP-3781711-A1 | SINGLE-STRANDED BREAK DETECTION IN DOUBLE-STRANDED DNA | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-02-24 | — | — | EP | claimed |
| WO-2019204585-A1 | SINGLE-STRANDED BREAK DETECTION IN DOUBLE-STRANDED DNA | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-10-24 | — | — | WO | claimed |
| US-20190292591-A1 | SYSTEMS AND METHODS FOR DETERMINING GENETIC DATA | Genia Technologies, Inc. (US) | 2019-09-26 | — | — | US | claimed |
| US-7374882-B2 | Method for base sequencing and biologically active nucleic acids | RIKEN (JP) | 2008-05-20 | — | — | US | claimed |
| JP-2008510765-A | — | — | 2008-04-10 | — | — | JP | claimed |
| EP-1784399-A2 | PYRIMIDINE DERIVATIVES | Novartis AG (CH) | 2007-05-16 | — | — | EP | claimed |
| WO-2006021457-A2 | PYRIMIDINE DERIVATIVES | NOVARTIS AG (CH) | 2006-03-02 | — | — | WO | claimed |
| US-20040115665-A1 | Method for base sequencing and biologically active nucleic acids | RIKEN (JP) | 2004-06-17 | — | — | US | claimed |
| JP-2004514440-A | — | — | 2004-05-20 | — | — | JP | claimed |
| US-20040077004-A1 | Use of nucleotide analogs in the analysis of oligonucleotide mixtures and highly multiplexed nucleic acid sequencing | TRUSTEES OF BOSTON UNIVERSITY, THE | 2004-04-22 | — | — | US | claimed |
| US-6660229-B2 | Synthesizing extension products of the target nucleic acid in the presence of chain terminating nucleotides and mass-matched nucleotides; determining the mass of each extension product; and calculating a mass shift | THE TRUSTEES OF BOSTON UNIVERSITY | 2003-12-09 | — | — | US | claimed |
| EP-1348035-A2 | METHOD FOR BASE SEQUENCING AND BIOLOGICALLY ACTIVE NUCLEIC ACIDS | Riken (JP) | 2003-10-01 | — | — | EP | claimed |
| WO-2002044195-A2 | METHOD FOR BASE SEQUENCING AND BIOLOGICALLY ACTIVE NUCLEIC ACIDS | RIKEN (JP) | 2002-06-06 | — | — | WO | claimed |