Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.45 |
| ▸ | BACE1 | P56817 | 5/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8241316 | 0.97 | ACHE (0.43) | ACHEBACE1PDE10APDE1CPDGFRB | |
| SCHEMBL4761434 | 0.89 | ACHE (0.54) | ACHEBACE1PDE10APDE1CPDE3B | |
| SCHEMBL4761466 | 0.89 | ACHE (0.54) | ACHEBACE1PDE10APDE1CPDE3B | |
| SCHEMBL4761654 | 0.89 | ACHE (0.54) | ACHEBACE1PDE10APDE1CPDE3B | |
| SCHEMBL8247271 | 0.88 | ACHE (0.37) | ACHEBACE1PDE10APDE1CPDGFRB | |
| SCHEMBL4402335 | 0.85 | ENPP1 (0.50) | ACHEBACE1PDE10APDE1CPDGFRB | |
| SCHEMBL5466078 | 0.76 | ACHE (0.50) | ACHEBACE1PDE10APDE1CPDGFRB | |
| SCHEMBL8251276 | 0.68 | ACHE (0.39) | ACHEBACE1PDE10APDE1CPDGFRB | |
| SCHEMBL4761922 | 0.68 | ACHE (0.55) | ACHEBACE1PDE10APDE1CENPP1 | |
| SCHEMBL4762524 | 0.68 | ACHE (0.52) | ACHEBACE1PDE10APDE1CAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007022280-A1 | PHOSPHODIESTERASE 10 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |