Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 4/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL842298 | 0.93 | KMT2A (0.37) | KMT2AHDAC6KDM4EALDH1A1EPHX2 | |
| SCHEMBL10173243 | 0.91 | KMT2A (0.37) | KMT2AHDAC6KDM4EALDH1A1EPHX2 | |
| SCHEMBL16781650 | 0.76 | KMT2A (0.49) | KMT2AEPHX2 | |
| SCHEMBL16781651 | 0.76 | KMT2A (0.49) | KMT2AEPHX2 | |
| SCHEMBL16486347 | 0.75 | KMT2A (0.53) | KMT2AEPHX2 | |
| SCHEMBL16781639 | 0.71 | KMT2A (0.44) | KMT2AKDM4EEPHX2 | |
| SCHEMBL16781640 | 0.71 | KMT2A (0.44) | KMT2AKDM4EEPHX2 | |
| SCHEMBL1252591 | 0.70 | KMT2A (0.47) | KMT2AEPHX2OPRD1CXCR2 | |
| SCHEMBL14864719 | 0.70 | KMT2A (0.47) | KMT2AEPHX2OPRD1CXCR2 | |
| SCHEMBL27906755 | 0.70 | KMT2A (0.52) | KMT2AALDH1A1EPHX2CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007030080-A1 | HETEROCYCLIC COMPOUNDS | S*BIO PTE LTD (SG) | 2007-03-15 | — | — | WO | disclosed |