Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 15/20 | 0.65 |
| ▸ | ACE | P12821 | 12/20 | 0.65 |
| ▸ | ACE2 | Q9BYF1 | 9/20 | 0.65 |
| ▸ | CPA1 | P15085 | 8/20 | 0.65 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8255494 | 0.92 | MME (0.62) | MMEACEACE2CPA1FOLH1 | |
| SCHEMBL8258735 | 0.92 | MME (0.62) | MMEACEACE2CPA1FOLH1 | |
| SCHEMBL8257978 | 0.92 | MME (0.62) | MMEACEACE2CPA1FOLH1 | |
| SCHEMBL5869326 | 0.92 | MME (0.62) | MMEACEACE2CPA1FOLH1 | |
| SCHEMBL5869343 | 0.91 | MME (0.55) | MMEACEACE2CPA1FOLH1 | |
| SCHEMBL5869386 | 0.91 | MME (0.55) | MMEACEACE2CPA1FOLH1 | |
| SCHEMBL5869380 | 0.91 | MME (0.55) | MMEACEACE2CPA1FOLH1 | |
| SCHEMBL5869467 | 0.90 | MME (0.54) | MMEACEACE2CPA1FOLH1 | |
| SCHEMBL5869450 | 0.90 | MME (0.54) | MMEACEACE2CPA1FOLH1 | |
| SCHEMBL5869454 | 0.90 | MME (0.54) | MMEACEACE2CPA1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082496-A1 | ACE-2 modulating compounds and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082496-A1 | ACE-2 modulating compounds and methods of use thereof | ACE, ACE2, AGTR2 | MME 11/4885ACE 1/4885ACE2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.