Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1521772 | 0.82 | BACE1 (0.60) | BACE1CTSD | |
| SCHEMBL8237271 | 0.81 | BACE1 (0.50) | BACE1CTSD | |
| SCHEMBL1521904 | 0.80 | BACE1 (0.39) | BACE1CTSD | |
| SCHEMBL1521718 | 0.79 | BACE1 (0.59) | BACE1CTSD | |
| SCHEMBL1522064 | 0.72 | BACE1 (0.57) | BACE1CTSD | |
| SCHEMBL4697454 | 0.71 | BACE1 (0.73) | BACE1CTSD | |
| SCHEMBL4890232 | 0.71 | ADRA2A (0.39) | BACE1CTSD | |
| SCHEMBL8281569 | 0.70 | BACE1 (0.73) | BACE1CTSD | |
| SCHEMBL4698668 | 0.70 | BACE1 (0.73) | BACE1CTSD | |
| SCHEMBL1521835 | 0.70 | BACE1 (0.57) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047305-A1 | METHODS OF TREATING AMYLOIDOSIS USING CYCLOPROPYL DERIVATIVE ASPARTYL PROTEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2007-04-26 | — | — | WO | disclosed |