Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7547537 | 0.78 | BACE1 (0.33) | BACE1HCAR3HCAR2 | |
| SCHEMBL13759871 | 0.72 | HCAR3 (0.34) | BACE1HCAR3HCAR2 | |
| SCHEMBL7540004 | 0.68 | BACE1 (0.35) | BACE1 | |
| SCHEMBL8246380 | 0.68 | BACE1 (0.31) | BACE1HCAR3HCAR2 | |
| SCHEMBL8245196 | 0.68 | BACE1 (0.36) | BACE1 | |
| SCHEMBL7543400 | 0.67 | BACE1 (0.32) | BACE1HCAR3HCAR2 | |
| SCHEMBL12172348 | 0.66 | BACE1 (0.33) | BACE1HCAR3HCAR2 | |
| SCHEMBL8246383 | 0.66 | BACE1 (0.34) | BACE1 | |
| SCHEMBL7599897 | 0.65 | BACE1 (0.43) | BACE1KMT2A | |
| SCHEMBL7600011 | 0.65 | BACE1 (0.42) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006138265-A2 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS, PREPARATION AND USE THEREOF | SCHERING CORPORATION (US) | 2006-12-28 | — | — | WO | disclosed |