SCHEMBL824903

SCHEMBL824903

C=C(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 1.00
HSD17B10 Q99714 4/20 1.00
HTT P42858 2/20 1.00
GFER P55789 1/20 1.00
GPR55 Q9Y2T6 1/20 1.00
LMNA P02545 5/20 0.53
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
CA1 P00915 3/20 0.53
CA2 P00918 3/20 0.53
CYP3A4 P08684 3/20 0.53
ALOX15 P16050 3/20 0.53
HIF1A Q16665 3/20 0.53
HPGD P15428 2/20 0.53
CA12 O43570 2/20 0.53
CA3 P07451 2/20 0.53
TYR P14679 2/20 0.53
CA4 P22748 2/20 0.53
CA5A P35218 2/20 0.53
CA9 Q16790 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10942166 1.00 MAPT (1.00) MAPTHSD17B10HTTGFERGPR55
SCHEMBL715505 0.89 MAPT (0.79) MAPTHSD17B10HTTGFERGPR55
SCHEMBL6795420 0.87 MAPT (0.75) MAPTHSD17B10HTTGFERGPR55
SCHEMBL20622470 0.87 MAPT (0.75) MAPTHSD17B10HTTGFERGPR55
SCHEMBL7685490 0.87 MAPT (0.75) MAPTHSD17B10HTTGFERGPR55
SCHEMBL13461740 0.87 MAPT (0.75) MAPTHSD17B10HTTGFERGPR55
SCHEMBL10441411 0.87 MAPT (0.75) MAPTHSD17B10HTTGFERGPR55
SCHEMBL10938928 0.84 MAPT (0.71) MAPTHSD17B10HTTGFERGPR55
SCHEMBL10936761 0.81 MAPT (0.67) MAPTHSD17B10HTTGFERGPR55
SCHEMBL10441340 0.81 HSD17B10 (0.65) MAPTHSD17B10HTTGFERGPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0130512-B1 BORON- AND NITROGEN-CONTAINING COMPOSITIONS AND THEIR USE IN POLYCARBONATE AND POLYESTER-POLYCARBONATE SYNTHESIS GENERAL ELECTRIC COMPANY (US) 1988-10-12 EP claimed
US-4163833-A FROM BISPHENOL, ALKALI METAL HYDROXIDE, WATER, METHYLENE HALIDE, PHASE TRANSFER CATALYST GENERAL ELECTRIC COMPANY (US) 1979-08-07 US claimed
EP-4259678-A1 POLYFUNCTIONAL HYDRAZIDE CROSSLINKER PPG Industries Ohio Inc. (US) 2023-10-18 EP disclosed
EP-3261814-B1 A PROCESS FOR MANUFACTURING A FIBER REINFORCED COMPOSITE ARTICLE, THE COMPOSITE ARTICLE OBTAINED AND THE USE THEREOF HUNTSMAN ADV MAT LICENSING SWITZERLAND GMBH (CH) 2023-04-19 EP disclosed
US-11525054-B2 Thermosetting epoxy resin composition for the preparation of articles for electrical engineering, and the articles obtained therefrom Huntsman Advanced Materials Licensing (CH) GmbH (CH) 2022-12-13 US disclosed
WO-2022125866-A1 POLYFUNCTIONAL HYDRAZIDE CROSSLINKER PPG INDUSTRIES OHIO, INC. (US) 2022-06-16 WO disclosed
US-11325326-B2 Process for manufacturing a fiber reinforced composite article, the composite article obtained and the use thereof HUNTSMAN INTERNATIONAL LLC (US) 2022-05-10 US disclosed
US-20220040353-A1 DEODORANT-CONTAINING WORKING FLUID, METHOD FOR MANUFACTURING DEODORIZING PRODUCT, DEODORIZING FILTER MEDIUM, DEODORIZING FILTER UNIT, AND DEODORIZING DEVICE TOAGOSEI CO., LTD. (JP) 2022-02-10 US disclosed
EP-3275002-B2 A PROCESS FOR THE PREPARATION OF INSULATION SYSTEMS FOR ELECTRICAL ENGINEERING, AND THE USE THEREOF HUNTSMAN ADV MAT LICENSING SWITZERLAND GMBH (CH) 2022-01-19 EP disclosed
WO-2021211182-A1 COMPOSITIONS CONTAINING THERMALLY CONDUCTIVE FILLERS PPG INDUSTRIES OHIO, INC. (US) 2021-10-21 WO disclosed
EP-3856817-A1 ONE-PART THERMALLY CURABLE COMPOSITION 3M Innovative Properties Company (US) 2021-08-04 EP disclosed
US-5081298-A Bis(pentaalkylguanidinium) alkane salts as phase transfer catalysts GENERAL ELECTRIC COMPANY (US) 1992-01-14 US disclosed
EP-0280403-B1 PROCESS FOR DEARYLATION OF ALKYLENEBISPHENOLS AND ALKYLTRISPHENOLS HOECHST CELANESE CORPORATION (US) 1991-12-11 EP disclosed
EP-0441648-A1 Purification of 1,1,1-tris(4'-hydroxyphenyl)ethane HOECHST CELANESE CORPORATION (US) 1991-08-14 EP disclosed
US-4992598-A Washing, isolating, filtering, rinsing and precipitating HOECHST CELANESE CORPORATION (US) 1991-02-12 US disclosed
EP-0130512-B1 BORON- AND NITROGEN-CONTAINING COMPOSITIONS AND THEIR USE IN POLYCARBONATE AND POLYESTER-POLYCARBONATE SYNTHESIS GENERAL ELECTRIC COMPANY (US) 1988-10-12 EP disclosed
EP-0280403-A1 Process for dearylation of alkylenebisphenols and alkyltrisphenols HOECHST CELANESE CORPORATION (US) 1988-08-31 EP disclosed
US-4754081-A Process for dearylation of alkylenebisphenols and alkyltrisphenols HOECHST CELANESE CORPORATION (US) 1988-06-28 US disclosed
EP-0024914-B1 TWO-COMPONENT RESIN COATING SYSTEMS AND COMPOSITIONS AND COATING PROCESSES USING THEM CELANESE CORPORATION (US) 1983-07-27 EP disclosed
US-3933690-A Dihalobutenediol containing urethane foam compositions ICI UNITED STATES INC. (US) 1976-01-20 US disclosed