Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.50 |
| ▸ | ACE | P12821 | 4/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | CPA1 | P15085 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CFD | P00746 | 1/20 | 0.45 |
| ▸ | F11 | P03951 | 1/20 | 0.45 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5869481 | 1.00 | SLC1A5 (0.52) | SLC1A5ACE2ACEMMECPA1 | |
| SCHEMBL5870306 | 0.83 | NR4A2 (0.53) | ACE2ACEMMECPA1MAPK1 | |
| SCHEMBL5870499 | 0.83 | NR4A2 (0.53) | ACE2ACEMMECPA1MAPK1 | |
| SCHEMBL5870305 | 0.83 | NR4A2 (0.53) | ACE2ACEMMECPA1MAPK1 | |
| SCHEMBL8249919 | 0.80 | MAPT (0.43) | ACE2ACEMMECPA1PDCD1 | |
| SCHEMBL5870095 | 0.80 | MAPT (0.43) | ACE2ACEMMECPA1PDCD1 | |
| SCHEMBL8250493 | 0.79 | ACE2 (0.48) | ACE2ACEMMECPA1MAPK1 | |
| SCHEMBL5869280 | 0.79 | ACE2 (0.48) | ACE2ACEMMECPA1MAPK1 | |
| SCHEMBL20514021 | 0.78 | SLC1A5 (0.71) | SLC1A5ENPP2CARM1PRMT1CFD | |
| SCHEMBL18342613 | 0.78 | SLC1A5 (0.71) | SLC1A5ENPP2CARM1PRMT1CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082496-A1 | ACE-2 modulating compounds and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. | 2004-04-29 | — | — | US | disclosed |
| US-20040082496-A1 | ACE-2 modulating compounds and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082496-A1 | ACE-2 modulating compounds and methods of use thereof | ACE, ACE2, AGTR2 | SLC1A5 2131/4885ACE2 2/4885ACE 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.