SCHEMBL825003

SCHEMBL825003

CC(C)c1cc(Cl)cc(Cc2cc(Br)cc(Cl)c2O)c1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.51
GABRB1 P18505 3/20 0.51
HSP90AA1 P07900 1/20 0.45
CYP2C9 P11712 3/20 0.40
HSD17B10 Q99714 3/20 0.40
CYP1A2 P05177 3/20 0.40
CYP2C19 P33261 2/20 0.40
CYP3A4 P08684 2/20 0.40
CYP2D6 P10635 1/20 0.40
HIF1A Q16665 2/20 0.38
HPGD P15428 2/20 0.37
ALDH1A1 P00352 2/20 0.37
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
GFER P55789 1/20 0.36
KMT2A Q03164 1/20 0.36
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
PRMT1 Q99873 1/20 0.34
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69737 0.86 GABRA1 (0.69) GABRA1GABRB1HSP90AA1CYP2C9HSD17B10
SCHEMBL8822890 0.80 HSP90AA1 (0.48) HSP90AA1CYP2C9HSD17B10CYP1A2CYP2C19
SCHEMBL13550802 0.78 HSP90AA1 (0.46) HSP90AA1CYP2C9HSD17B10CYP1A2CYP2C19
SCHEMBL9967745 0.77 GABRA1 (0.72) GABRA1GABRB1CYP2C9HSD17B10CYP1A2
SCHEMBL14706184 0.74 GABRA1 (0.67) GABRA1GABRB1CYP2C9HSD17B10CYP2C19
SCHEMBL12767956 0.73 GABRA1 (0.78) GABRA1GABRB1HSD17B10CYP1A2CYP3A4
SCHEMBL67608 0.73 HSP90AA1 (0.74) HSP90AA1CYP2C9HSD17B10CYP1A2CYP2C19
SCHEMBL16600020 0.73 GABRA1 (0.39) GABRA1GABRB1CYP2C9HSD17B10CYP1A2
SCHEMBL11590889 0.71 TSHR (0.37) GABRA1GABRB1HSP90AA1CYP2C9HSD17B10
SCHEMBL11679871 0.71 GABRA1 (0.47) GABRA1GABRB1HSP90AA1CYP2C9HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2714763-B1 EPOXY RESINS WITH HIGH THERMAL STABILITY AND TOUGHNESS HUNTSMAN ADVANCED MAT AMERICAS LLC (US) 2017-03-01 EP disclosed
US-9051498-B2 Epoxy resins with high thermal stability and toughness HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2015-06-09 US disclosed
US-9051498-B2 Epoxy resins with high thermal stability and toughness HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2015-06-09 US disclosed
US-9051415-B2 Epoxy resins with high thermal stability and toughness HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2015-06-09 US disclosed
US-9051415-B2 Epoxy resins with high thermal stability and toughness HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2015-06-09 US disclosed
US-20140296447-A1 Epoxy Resins With High Thermal Stability and Toughness Huntsman Advanced Materials Americans LLC (US) 2014-10-02 US disclosed
US-20140296447-A1 Epoxy Resins With High Thermal Stability and Toughness Huntsman Advanced Materials Americans LLC (US) 2014-10-02 US disclosed
US-20140069583-A1 Epoxy Resins With High Thermal Stability and Toughness HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2014-03-13 US disclosed
US-20140069583-A1 Epoxy Resins With High Thermal Stability and Toughness HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2014-03-13 US disclosed
US-8142101-B2 Hydrocarbon-adsorbing porous pavement structure Reynolds Presto Products Inc. (US) 2012-03-27 US disclosed
US-8043982-B2 Basalt particle-containing compositions and articles for protective coatings and ballistic shield mats/tiles/protective building components U.S. WIND FARMING, INC. (US) 2011-10-25 US disclosed
US-8043982-B2 Basalt particle-containing compositions and articles for protective coatings and ballistic shield mats/tiles/protective building components U.S. WIND FARMING, INC. (US) 2011-10-25 US disclosed
US-20100285269-A1 BASALT PARTICLE-CONTAINING COMPOSITIONS AND ARTICLES FOR PROTECTIVE COATINGS AND BALLISTIC SHIELD MATS/TILES/PROTECTIVE BUILDING COMPONENTS U.S. WIND FARMING, INC. (US) 2010-11-11 US disclosed
US-20100285269-A1 BASALT PARTICLE-CONTAINING COMPOSITIONS AND ARTICLES FOR PROTECTIVE COATINGS AND BALLISTIC SHIELD MATS/TILES/PROTECTIVE BUILDING COMPONENTS U.S. WIND FARMING, INC. (US) 2010-11-11 US disclosed
US-20090067924-A1 HYDROCARBON-ADSORBING POROUS PAVEMENT STRUCTURE KAUL CORPORATION (US) 2009-03-12 US disclosed
US-20090067924-A1 HYDROCARBON-ADSORBING POROUS PAVEMENT STRUCTURE KAUL CORPORATION (US) 2009-03-12 US disclosed
US-20070224401-A1 Basalt particle-containing articles for ballistic shield mats/tiles/protective building components U.S. WIND FARMING INC. (US) 2007-09-27 US disclosed
US-20070224401-A1 Basalt particle-containing articles for ballistic shield mats/tiles/protective building components U.S. WIND FARMING INC. (US) 2007-09-27 US disclosed
US-20070154643-A1 Extrusion coating compositions and method VALSPAR SOURCING, INC. (US) 2007-07-05 US disclosed
US-20070154643-A1 Extrusion coating compositions and method VALSPAR SOURCING, INC. (US) 2007-07-05 US disclosed