⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10291869 | 1.00 | — | — | |
| SCHEMBL10056813 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL8127228 | 0.97 | — | — | |
| SCHEMBL9617308 | 0.85 | LMNA (0.43) | — | |
| SCHEMBL18286558 | 0.85 | LMNA (0.43) | — | |
| SCHEMBL23235081 | 0.82 | SLC7A5 (0.43) | — | |
| SCHEMBL12292990 | 0.82 | SLC7A5 (0.43) | — | |
| SCHEMBL12940444 | 0.80 | — | — | |
| SCHEMBL13979525 | 0.80 | — | — | |
| SCHEMBL23749632 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462816-A | Hecogenin derivative with antitumor activity and preparation method and application thereof | 齐齐哈尔医学院 | 2025-02-18 | — | — | CN | disclosed |
| CN-117805280-A | Ultrahigh performance liquid-mass spectrometry detection method for internal and external components of classical Ming Fang Xiaoxiangqi decoction | 陕西省中医药研究院 | 2024-04-02 | — | — | CN | disclosed |
| US-20240067702-A1 | LACTAM-MODIFIED POLYPEPTIDE COMPOUNDS | TONGHUA DONGBAO PHARMACEUTICAL CO., LTD. (CN) | 2024-02-29 | — | — | US | disclosed |
| US-11771688-B2 | Pyridine derivatives substituted by heterocyclic ring and amino group | AMPLYX PHARMACEUTICALS, INC. (US) | 2023-10-03 | — | — | US | disclosed |
| US-11771688-B2 | Pyridine derivatives substituted by heterocyclic ring and amino group | AMPLYX PHARMACEUTICALS, INC. (US) | 2023-10-03 | — | — | US | disclosed |
| US-11739074-B2 | Ras inhibitors | Revolution Medicines, Inc. (US) | 2023-08-29 | — | — | US | disclosed |
| US-20230233569-A1 | METHODS FOR DELAYING, PREVENTING, AND TREATING ACQUIRED RESISTANCE TO RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-07-27 | — | — | US | disclosed |
| EP-4209483-A1 | PRODRUG MODULATORS OF THE INTEGRATED STRESS PATHWAY | Calico Life Sciences LLC (US) | 2023-07-12 | — | — | EP | disclosed |
| EP-3182962-B1 | COMPOSITIONS AND USES OF AMIDINE DERIVATIVES | BIOCRYST PHARM INC (US) | 2023-06-07 | — | — | EP | disclosed |
| US-20230165970-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS | CIDARA THERAPEUTICS, INC. | 2023-06-01 | — | — | US | disclosed |
| US-20070142334-A1 | INHIBITORS OF p38 | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2007-06-21 | — | — | US | disclosed |
| CN-1308301-C | Pleuromutilin derivatives with antibacterial activity | BIOCHEMIE GMBH (CH) | 2007-04-04 | — | — | CN | disclosed |
| US-7186737-B2 | Inhibitors of p38 | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2007-03-06 | — | — | US | disclosed |
| US-7186737-B2 | Inhibitors of p38 | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2007-03-06 | — | — | US | disclosed |
| US-20070043098-A1 | Process for the preparation of tetrazole derivatives from organo boron and organo aluminium azides | NOVARTIS PHARMACEUTICALS CORPORATION | 2007-02-22 | — | — | US | disclosed |
| US-6753445-B2 | 14-O-((CYCLOALKYL-SULFANYL)ACETYL)-, 14-O-((CYCLOALKYL-ALKYL-SULFANYL)ACETYL)-, 14-O-((CYCLOALKOXY)ACETYL)- AND 14-O-((CYCLOALKYL-ALKOXY) ACETYL) MUTILINS; MICROBIOCIDES | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2004-06-22 | — | — | US | disclosed |
| CN-1441778-A | Pleuromutilin derivatives having antibacterial activity | BIOCHEMIE GMBH (AT) | 2003-09-10 | — | — | CN | disclosed |
| US-20030162831-A1 | Pleuromutilin derivatives having antibacterial activity | Nabriva Therapeutics GmbH (AT) | 2003-08-28 | — | — | US | disclosed |
| EP-1305282-A1 | PLEUROMUTILIN DERIVATIVES HAVING ANTIBACTERIAL ACTIVITY | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002004414-A1 | PLEUROMUTILIN DERIVATIVES HAVING ANTIBACTERIAL ACTIVITY | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2002-01-17 | — | — | WO | disclosed |