Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1167064 | 0.97 | EPHX1 (0.45) | EPHX1TSHRCYP3A4CYP2C19CNR2 | |
| SCHEMBL1536518 | 0.97 | EPHX1 (0.45) | EPHX1TSHRCYP3A4CYP2C19CNR2 | |
| SCHEMBL8243961 | 0.95 | EPHX1 (0.47) | EPHX1TSHRCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL20456806 | 0.93 | EPHX1 (0.36) | EPHX1TSHRCYP3A4CYP2C19CNR2 | |
| SCHEMBL20456807 | 0.93 | EPHX1 (0.36) | EPHX1TSHRCYP3A4CYP2C19CNR2 | |
| SCHEMBL15219814 | 0.87 | EPHX1 (0.41) | EPHX1TSHRCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL12401411 | 0.85 | EPHX1 (0.40) | EPHX1TSHRCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL14432924 | 0.84 | CNR2 (0.33) | EPHX1CNR2ALDH1A1SMN1; SMN2CA2 | |
| SCHEMBL14943351 | 0.83 | EPHX1 (0.45) | EPHX1TSHRCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL12335718 | 0.83 | EPHX1 (0.45) | EPHX1TSHRCYP3A4CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229818-A1 | Hepatitis C inhibitor compound | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-11-18 | — | — | US | disclosed |
| US-20040229818-A1 | Hepatitis C inhibitor compound | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229818-A1 | Hepatitis C inhibitor compound | HAVCR2, GTF3C1, RNASE1 | EPHX1 1187/4885TSHR 3799/4885CYP3A4 520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.